HPL Fat-Dissolving Injection: How It Works at 365mc

HPL is a non-surgical fat-dissolving injection designed for localized stubborn fat. See how 365mc’s steroid-free HPL formula works and which areas it may treat.
Stubborn fat on the lower belly, inner thighs, and arms rarely responds to diet and exercise, no matter how disciplined you are. For people who want a non-surgical option before considering liposuction, HPL — Hypotonic Pharmacological Lipodissolution — is one of the most asked-about fat-dissolving injections. As the most chosen body contouring clinic in Asia, 365mc offers HPL for localized, hard-to-shift fat.
How does HPL dissolve fat?
HPL works through osmotic pressure, not heat or surgery. A hypotonic, saline-based solution is injected into the fat layer, where the difference in concentration draws water into the fat cells. The cells swell until their membranes break down, and the released contents are then cleared naturally through the lymphatic system and kidneys. Because there is no incision and no general anesthesia, HPL is considered a non-surgical fat reduction option with same-day return to routine. Each session takes roughly 30–40 minutes, spaced about 7–10 days apart.
Is 365mc's HPL safe? The steroid-free difference
365mc uses a steroid-free HPL formula, which matters more than many people realize. Some fat-dissolving injections contain steroids that can disturb the body's hormonal balance, and a steroid-free approach avoids that concern. As with any injection, temporary responses are normal: the treated area may swell for about 24 hours, a small amount of pink, watery fluid may drain, and mild dizziness or increased urination can occur as the solution is absorbed and cleared. These effects vary from person to person and ease on their own.
HPL or LAMS: which fits stubborn fat?
HPL gently dissolves fat across a wide area, while LAMS — Local Anesthetic Minimal-Invasive Liposuction directly extracts fat in about 10 minutes without general anesthesia. Like liposuction, LAMS removes the fat cells themselves: after a tunneling step, fat is drawn out through a syringe so you can see what's removed, then a fat-dissolving solution is injected to smooth the overall line. Beyond LAMS, 365mc also offers options such as O-Slim Shot and Stem Cell, so a consultation is the clearest way to find what fits your body.
Talk to the 365mc team
Choosing between a fat-dissolving injection and direct extraction is easier with expert input on your specific areas and goals.
Consultation inquiry
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